Information

Name

Kessler, John, MD

Title

Benjamin Boshes Professor and Chair

Email

jakessler@northwestern.edu

Office Phone

312-908-5035

Department

Neurology

Office

Ward 10-185 Chicago

Areas of Research

Molecular Neuroscience, Neurobiology of Disease

NU Scholar Profile

http://www.scholars.northwestern.edu/expert.asp?u_id=1186

Recent Publications on PubMed

http://www.ncbi.nlm.nih.gov/pubmed?term=Kessler%2C%20John%5BFull%20Author%20Name%5D&cmd=DetailsSearch

Current Research

Current Research

Our laboratory focuses on the biology of embryonic stem cells and neural stem cells. We are interested in defining mechanisms regulating neuronal and glial differentiation of stem/progenitor cells, and on understanding how growth factors promote neuronal and glial survival and phenotypic expression. These studies seek to identify the cytokines that regulate stem cell proliferation and differentiation, to define the intracellular signals that transduce their effects, and to understand how the effects of different growth factors are integrated by the progenitor cell. Although the principal focus of these studies is on definition of mechanisms underlying stem cell differentiation, a significant effort is also devoted to applying molecular neurobiology to clinical problems. Specifically we are developing techniques for the treatment of spinal cord injury and stroke.